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Evidence for anti-angiogenic and pro-survival functions of the cerebral cavernous malformation protein 3

Mutations in CCM1, CCM2, or CCM3 lead to cerebral cavernous malformations, one of the most common hereditary vascular diseases of the brain. Endothelial cells within these lesions are the main disease compartments. Here, we show that adenoviral CCM3 expression inhibits endothelial cell migration, pr...

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Detalhes bibliográficos
Main Authors: Schleider, Elisa, Stahl, Sonja, Wüstehube, Joycelyn, Walter, Ulrich, Fischer, Andreas, Felbor, Ute
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3029799/
https://ncbi.nlm.nih.gov/pubmed/20862502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10048-010-0261-6
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