Embryonic day 9 yolk sac and intra-embryonic hemogenic endothelium independently generate a B-1 and marginal zone progenitor lacking B-2 potential

The majority of B lymphocytes in the adult mouse are generated in the bone marrow from hematopoietic stem cells (HSCs) that first appear in the aorta-gonado-mesonephros region of the fetus on embryonic day (E) 10.5–11. Comparatively less is known about B-cell development during embryogenesis. For ex...

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Bibliographic Details
Main Authors: Yoshimoto, Momoko, Montecino-Rodriguez, Encarnacion, Ferkowicz, Michael J., Porayette, Prashanth, Shelley, W. Christopher, Conway, Simon J., Dorshkind, Kenneth, Yoder, Mervin C.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2011
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3029764/
https://ncbi.nlm.nih.gov/pubmed/21209332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1015841108
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