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Copper resistance is essential for virulence of Mycobacterium tuberculosis

Copper (Cu) is essential for many biological processes, but is toxic when present in excessive amounts. In this study, we provide evidence that Cu plays a crucial role in controlling tuberculosis. A Mycobacterium tuberculosis (Mtb) mutant lacking the outer membrane channel protein Rv1698 accumulated...

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Detalhes bibliográficos
Main Authors: Wolschendorf, Frank, Ackart, David, Shrestha, Tej B., Hascall-Dove, Laurel, Nolan, Scott, Lamichhane, Gyanu, Wang, Ying, Bossmann, Stefan H., Basaraba, Randall J., Niederweis, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3029754/
https://ncbi.nlm.nih.gov/pubmed/21205886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1009261108
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