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Augmented glucose-induced insulin release in mice lacking G(o2), but not G(o1) or G(i) proteins

Insulin secretion by pancreatic β cells is a complex and highly regulated process. Disruption of this process can lead to diabetes mellitus. One of the various pathways involved in the regulation of insulin secretion is the activation of heterotrimeric G proteins. Bordetella pertussis toxin (PTX) pr...

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Autori principali: Wang, Ying, Park, Sangeun, Bajpayee, Neil S., Nagaoka, Yoshiko, Boulay, Guylain, Birnbaumer, Lutz, Jiang, Meisheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3029743/
https://ncbi.nlm.nih.gov/pubmed/21220323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018903108
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