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Crystallographic and online spectral evidence for role of conformational change and conserved water in cytochrome oxidase proton pump
Crystal structures in both oxidized and reduced forms are reported for two bacterial cytochrome c oxidase mutants that define the D and K proton paths, showing conformational change in response to reduction and the loss of strategic waters that can account for inhibition of proton transfer. In the o...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3029696/ https://ncbi.nlm.nih.gov/pubmed/21205904 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1012846108 |
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