Pravastatin induces placental growth factor (PGF) and ameliorates preeclampsia in a mouse model

Preeclampsia is a relatively common pregnancy-related disorder. Both maternal and fetal lives will be endangered if it proceeds unabated. Recently, the placenta-derived anti-angiogenic factors, such as soluble fms-like tyrosine kinase-1 (sFLT1) and soluble endoglin (sENG), have attracted attention i...

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Main Authors: Kumasawa, Keiichi, Ikawa, Masahito, Kidoya, Hiroyasu, Hasuwa, Hidetoshi, Saito-Fujita, Tomoko, Morioka, Yuka, Takakura, Nobuyuki, Kimura, Tadashi, Okabe, Masaru
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2011
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3029692/
https://ncbi.nlm.nih.gov/pubmed/21187414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1011293108
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