Impaired autophagy by soluble endoglin, under physiological hypoxia in early pregnant period, is involved in poor placentation in preeclampsia

In early pregnancy, trophoblasts and the fetus experience hypoxic and low-nutrient conditions; nevertheless, trophoblasts invade the uterine myometrium up to one third of its depth and migrate along the lumina of spiral arterioles, replacing the maternal endothelial lining. Here, we showed that auto...

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Autori principali: Nakashima, Akitoshi, Yamanaka-Tatematsu, Mikiko, Fujita, Naonobu, Koizumi, Keiichi, Shima, Tomoko, Yoshida, Toshiko, Nikaido, Toshio, Okamoto, Aikou, Yoshimori, Tamotsu, Saito, Shigeru
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2013
Soggetti:
Basic Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3590252/
https://ncbi.nlm.nih.gov/pubmed/23321791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.22927
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