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Inhibition of Legionella pneumophila growth by gamma interferon in permissive A/J mouse macrophages: role of reactive oxygen species, nitric oxide, tryptophan, and iron(III).

A/J mouse macrophages infected with Legionella pneumophila and treated with gamma interferon (IFN-gamma) in vitro developed potent antimicrobial activity. This antilegionella activity was independent of the macrophage capacity to generate reactive oxygen intermediates, since the oxygen radical scave...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Gebran, S J, Yamamoto, Y, Newton, C, Klein, T W, Friedman, H
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC302946/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8039889/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.62.8.3197-3205.1994
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