Allelic Diversity of the Plasmodium falciparum Erythrocyte Membrane Protein 1 Entails Variant-Specific Red Cell Surface Epitopes

The clonally variant Plasmodium falciparum PfEMP1 adhesin is a virulence factor and a prime target of humoral immunity. It is encoded by a repertoire of functionally differentiated var genes, which display architectural diversity and allelic polymorphism. Their serological relationship is key to und...

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Detalhes bibliográficos
Main Authors: Vigan-Womas, Inès, Guillotte, Micheline, Juillerat, Alexandre, Vallieres, Cindy, Lewit-Bentley, Anita, Tall, Adama, Baril, Laurence, Bentley, Graham A., Mercereau-Puijalon, Odile
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3029348/
https://ncbi.nlm.nih.gov/pubmed/21298021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016544
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