The humoral response to Plasmodium falciparum VarO rosetting variant and its association with protection against malaria in Beninese children

BACKGROUND: The capacity of Plasmodium falciparum-infected erythrocytes to bind uninfected erythrocytes (rosetting) is associated with severe malaria in African children. Rosetting is mediated by a subset of the variant surface antigens PfEMP1 targeted by protective antibody responses. Analysis of t...

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Main Authors: Vigan-Womas, Inès, Lokossou, Adjimon, Guillotte, Micheline, Juillerat, Alexandre, Bentley, Graham, Garcia, André, Mercereau-Puijalon, Odile, Migot-Nabias, Florence
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2010
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2959068/
https://ncbi.nlm.nih.gov/pubmed/20923548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-9-267
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