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HNF4alpha Dysfunction as a Molecular Rational for Cyclosporine Induced Hypertension

Induction of tolerance against grafted organs is achieved by the immunosuppressive agent cyclosporine, a prominent member of the calcineurin inhibitors. Unfortunately, its lifetime use is associated with hypertension and nephrotoxicity. Several mechanism for cyclosporine induced hypertension have be...

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Библиографические подробности
Главные авторы: Niehof, Monika, Borlak, Jürgen
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3029342/
https://ncbi.nlm.nih.gov/pubmed/21298017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016319
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