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HNF4alpha and HNF1alpha Dysfunction as a Molecular Rational for Cyclosporine Induced Posttransplantation Diabetes Mellitus

Posttransplantation diabetes mellitus (PTDM) is a frequent complication in immunosuppressive therapy. To better understand the molecular events associated with PTDM we investigated the effect of cyclosporine on expression and activity of hepatic nuclear factor (HNF)1alpha and 4alpha and on genes cod...

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Detalhes bibliográficos
Main Authors: Borlak, Jürgen, Niehof, Monika
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646130/
https://ncbi.nlm.nih.gov/pubmed/19252740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004662
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