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The Role of Histone H4 Biotinylation in the Structure of Nucleosomes

BACKGROUND: Post-translational modifications of histones play important roles in regulating nucleosome structure and gene transcription. It has been shown that biotinylation of histone H4 at lysine-12 in histone H4 (K12Bio-H4) is associated with repression of a number of genes. We hypothesized that...

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Detalhes bibliográficos
Main Authors: Filenko, Nina A., Kolar, Carol, West, John T., Smith, S. Abbie, Hassan, Yousef I., Borgstahl, Gloria E. O., Zempleni, Janos, Lyubchenko, Yuri L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3029316/
https://ncbi.nlm.nih.gov/pubmed/21298003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016299
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