Complete protection against Plasmodium yoelii by adoptive transfer of a CD8+ cytotoxic T-cell clone recognizing sporozoite surface protein 2.

BALB/c mice immunized with irradiated Plasmodium yoelii sporozoites produce antibodies and cytotoxic T lymphocytes against the circumsporozoite protein and against a 140-kDa protein, sporozoite surface protein 2 (PySSP2). Approximately 50% of mice immunized with P815 cells transfected with the gene...

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Pubblicato in:	Infect Immun
Autori principali:	Khusmith, S, Sedegah, M, Hoffman, S L
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1994
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC302907/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8005684/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.62.7.2979-2983.1994
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