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Matrix Domain Modulates HIV-1 Gag's Nucleic Acid Chaperone Activity via Inositol Phosphate Binding

Retroviruses replicate by reverse transcribing their single-stranded RNA genomes into double-stranded DNA using specific cellular tRNAs to prime cDNA synthesis. In HIV-1, human tRNA(3)(Lys) serves as the primer and is packaged into virions during assembly. The viral Gag protein is believed to chaper...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Jones, Christopher P., Datta, Siddhartha A. K., Rein, Alan, Rouzina, Ioulia, Musier-Forsyth, Karin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3028911/
https://ncbi.nlm.nih.gov/pubmed/21123373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01809-10
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