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Foamy Retrovirus Integrase Contains a Pol Dimerization Domain Required for Protease Activation
Unlike orthoretroviruses, foamy retroviruses (FV) synthesize Pol independently of Gag. The FV Pol precursor is cleaved only once between reverse transcriptase (RT) and integrase (IN) by the protease (PR), resulting in a PR-RT and an IN protein. Only the Pol precursor, not the cleaved subunits, is pa...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3028899/ https://ncbi.nlm.nih.gov/pubmed/21123385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01873-09 |
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