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Inhibition of Influenza Virus Infection in Human Airway Cell Cultures by an Antisense Peptide-Conjugated Morpholino Oligomer Targeting the Hemagglutinin-Activating Protease TMPRSS2

Influenza A viruses constitute a major and ongoing global public health concern. Current antiviral strategies target viral gene products; however, the emergence of drug-resistant viruses highlights the need for novel antiviral approaches. Cleavage of the influenza virus hemagglutinin (HA) by host ce...

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Main Authors: Böttcher-Friebertshäuser, Eva, Stein, David A., Klenk, Hans-Dieter, Garten, Wolfgang
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3028871/
https://ncbi.nlm.nih.gov/pubmed/21123387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01294-10
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