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Agglutination of Histoplasma capsulatum by IgG Monoclonal Antibodies against Hsp60 Impacts Macrophage Effector Functions

Histoplasma capsulatum can efficiently survive within macrophages, facilitating H. capsulatum translocation from the lung into the lymphatics and bloodstream. We have recently generated monoclonal antibodies (MAbs) to an H. capsulatum surface-expressed heat shock protein of 60 kDa (Hsp60) that modif...

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Bibliografski detalji
Glavni autori: Guimarães, Allan Jefferson, Frases, Susana, Pontes, Bruno, de Cerqueira, Mariana Duarte, Rodrigues, Marcio L., Viana, Nathan Bessa, Nimrichter, Leonardo, Nosanchuk, Joshua Daniel
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3028823/
https://ncbi.nlm.nih.gov/pubmed/21134968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00673-10
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