Agglutination of Histoplasma capsulatum by IgG Monoclonal Antibodies against Hsp60 Impacts Macrophage Effector Functions

Histoplasma capsulatum can efficiently survive within macrophages, facilitating H. capsulatum translocation from the lung into the lymphatics and bloodstream. We have recently generated monoclonal antibodies (MAbs) to an H. capsulatum surface-expressed heat shock protein of 60 kDa (Hsp60) that modif...

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Detalhes bibliográficos
Main Authors: Guimarães, Allan Jefferson, Frases, Susana, Pontes, Bruno, de Cerqueira, Mariana Duarte, Rodrigues, Marcio L., Viana, Nathan Bessa, Nimrichter, Leonardo, Nosanchuk, Joshua Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3028823/
https://ncbi.nlm.nih.gov/pubmed/21134968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00673-10
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