Agglutination of Histoplasma capsulatum by IgG Monoclonal Antibodies against Hsp60 Impacts Macrophage Effector Functions

Histoplasma capsulatum can efficiently survive within macrophages, facilitating H. capsulatum translocation from the lung into the lymphatics and bloodstream. We have recently generated monoclonal antibodies (MAbs) to an H. capsulatum surface-expressed heat shock protein of 60 kDa (Hsp60) that modif...

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Bibliographische Detailangaben
Hauptverfasser: Guimarães, Allan Jefferson, Frases, Susana, Pontes, Bruno, de Cerqueira, Mariana Duarte, Rodrigues, Marcio L., Viana, Nathan Bessa, Nimrichter, Leonardo, Nosanchuk, Joshua Daniel
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2011
Schlagworte:
Fungal and Parasitic Infections
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3028823/
https://ncbi.nlm.nih.gov/pubmed/21134968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00673-10
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