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The Antibiotic Monensin Causes Cell Cycle Disruption of Toxoplasma gondii Mediated through the DNA Repair Enzyme TgMSH-1

Monensin is a polyether ionophore antibiotic that is widely used in the control of coccidia in animals. Despite its significance in veterinary medicine, little is known about its mode of action and potential mechanisms of resistance in coccidian parasites. Here we show that monensin causes accumulat...

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Main Authors: Lavine, Mark D., Arrizabalaga, Gustavo
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology (ASM) 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3028789/
https://ncbi.nlm.nih.gov/pubmed/21098240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01092-10
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