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Disruption of a Mitochondrial MutS DNA Repair Enzyme Homolog Confers Drug Resistance in the Parasite Toxoplasma gondii
MutS homologs (MSHs) are critical components of the eukaryotic mismatch repair machinery. In addition to repairing mismatched DNA, mismatch repair enzymes are known in higher eukaryotes to directly signal cell cycle arrest and apoptosis in response to DNA damaging agents. Accordingly, mammalian cell...
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| Asıl Yazarlar: | , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2009
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2712120/ https://ncbi.nlm.nih.gov/pubmed/19291232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2009.06655.x |
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