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Tumor Necrosis Factor Alpha and Inflammation Disrupt the Polarity Complex in Intestinal Epithelial Cells by a Posttranslational Mechanism

Inflammatory processes disrupt the barrier function in epithelia. Increased permeability often leads to chronic of inflammation. Important among other cytokines, tumor necrosis factor alpha (TNF-α) initiates an NF-κB-mediated response that leads to upregulation of myosin light chain kinase (MLCK), a...

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Detalhes bibliográficos
Main Authors: Mashukova, Anastasia, Wald, Flavia A., Salas, Pedro J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3028658/
https://ncbi.nlm.nih.gov/pubmed/21135124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00811-10
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