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HBO1 Is Required for H3K14 Acetylation and Normal Transcriptional Activity during Embryonic Development
We report here that the MYST histone acetyltransferase HBO1 (histone acetyltransferase bound to ORC; MYST2/KAT7) is essential for postgastrulation mammalian development. Lack of HBO1 led to a more than 90% reduction of histone 3 lysine 14 (H3K14) acetylation, whereas no reduction of acetylation was...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3028655/ https://ncbi.nlm.nih.gov/pubmed/21149574 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00159-10 |
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