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Lipocalin-13 Regulates Glucose Metabolism by both Insulin-Dependent and Insulin-Independent Mechanisms

Insulin sensitivity is impaired in obesity, and insulin resistance is the primary risk factor for type 2 diabetes. Here we show that lipocalin-13 (LCN13), a lipocalin superfamily member, is a novel insulin sensitizer. LCN13 was secreted by multiple cell types. Circulating LCN13 was markedly reduced...

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Detalhes bibliográficos
Main Authors: Cho, Kae Won, Zhou, Yingjiang, Sheng, Liang, Rui, Liangyou
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3028623/
https://ncbi.nlm.nih.gov/pubmed/21135134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00459-10
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