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MRP2 and the Handling of Mercuric Ions in Rats Exposed Acutely to Inorganic and Organic Species of Mercury

Mercuric ions accumulate preferentially in renal tubular epithelial cells and bond with intracellular thiols. Certain metal-complexing agents have been shown to promote extraction of mercuric ions via the multidrug resistance-associated protein 2 (MRP2). Following exposure to a non-toxic dose of ino...

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Detalhes bibliográficos
Main Authors: Bridges, Christy C., Joshee, Lucy, Zalups, Rudolfs K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3028519/
https://ncbi.nlm.nih.gov/pubmed/21134393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2010.11.015
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