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MRP2 and the DMPS- and DMSA-Mediated Elimination of Mercury in TR(−) and Control Rats Exposed to Thiol S-Conjugates of Inorganic Mercury
Cysteine (Cys) and homocysteine (Hcy)-S-conjugates of inorganic mercury (Hg(2+)) are transportable species of Hg(2+) that are taken up readily by proximal tubular cells. The metal chelators, 2,3-dimercaptopropane-1-sulfonic acid (DMPS) and meso-2,3-dimercaptosuccinic acid (DMSA), have been used succ...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2734303/ https://ncbi.nlm.nih.gov/pubmed/18511429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfn107 |
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