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MRP2 and the DMPS- and DMSA-Mediated Elimination of Mercury in TR(−) and Control Rats Exposed to Thiol S-Conjugates of Inorganic Mercury

Cysteine (Cys) and homocysteine (Hcy)-S-conjugates of inorganic mercury (Hg(2+)) are transportable species of Hg(2+) that are taken up readily by proximal tubular cells. The metal chelators, 2,3-dimercaptopropane-1-sulfonic acid (DMPS) and meso-2,3-dimercaptosuccinic acid (DMSA), have been used succ...

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Podrobná bibliografie
Hlavní autoři: Bridges, Christy C., Joshee, Lucy, Zalups, Rudolfs K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2734303/
https://ncbi.nlm.nih.gov/pubmed/18511429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfn107
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