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An N-terminal Domain of Adenovirus Protein VI Fragments Membranes By Inducing Positive Membrane Curvature

Adenovirus (Ad) membrane penetration during cell entry is poorly understood. Here we show that antibodies which neutralize the membrane lytic activity of the Ad capsid protein VI interfere with Ad endosomal membrane penetration. In vitro studies using a peptide corresponding to an N-terminal amphipa...

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Autors principals: Maier, Oana, Galan, Debra L., Wodrich, Harald, Wiethoff, Christopher M.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3028504/
https://ncbi.nlm.nih.gov/pubmed/20409568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.03.043
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