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Interleukin-6 Enhances Glucose-Stimulated Insulin Secretion From Pancreatic β-Cells: Potential Involvement of the PLC-IP(3)–Dependent Pathway
OBJECTIVE: Interleukin-6 (IL-6) has a significant impact on glucose metabolism. However, the effects of IL-6 on insulin secretion from pancreatic β-cells are controversial. Therefore, we analyzed IL-6 effects on pancreatic β-cell functions both in vivo and in vitro. RESEARCH DESIGN AND METHODS: Firs...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Diabetes Association
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3028353/ https://ncbi.nlm.nih.gov/pubmed/21270264 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-0796 |
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