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Isolated imprinting mutation of the DLK1/GTL2 locus associated with a clinical presentation of maternal uniparental disomy of chromosome 14

The clinical phenotypes of maternal and paternal uniparental disomy of chromosome 14 (UPD14) are attributed to dysregulation of imprinted genes. A large candidate locus exists within 14q32, under the regulation of a paternally methylated intergenic differentially methylated region (IG-DMR). We prese...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Temple, I K, Shrubb, V, Lever, M, Bullman, H, Mackay, D J G
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Publishing Group 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3027731/
https://ncbi.nlm.nih.gov/pubmed/21731585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bcr.06.2009.1997
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