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Isolated imprinting mutation of the DLK1/GTL2 locus associated with a clinical presentation of maternal uniparental disomy of chromosome 14

The clinical phenotypes of maternal and paternal uniparental disomy of chromosome 14 (UPD14) are attributed to dysregulation of imprinted genes. A large candidate locus exists within 14q32, under the regulation of a paternally methylated intergenic differentially methylated region (IG‐DMR). We prese...

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Detalhes bibliográficos
Main Authors: Temple, I K, Shrubb, V, Lever, M, Bullman, H, Mackay, D J G
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597958/
https://ncbi.nlm.nih.gov/pubmed/17601927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2007.050807
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