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Effect of low doses of lipopolysaccharide prior to ozone exposure on bronchoalveolar lavage: Differences between wild type and surfactant protein A-deficient mice

BACKGROUND: Several aspects of the inflammatory response to a single insult, i.e., exposure to 2 ppm of ozone (O(3)) for 3 h or 6 h, are less pronounced in surfactant protein A deficient (SP-A −/−) mice (KO) than in wild type mice (WT). It was hypothesized that a mild insult, specifically low doses...

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Bibliographic Details
Main Authors: Haque, Rizwanul, Umstead, Todd M., Ahn, Kwangmi, Phelps, David S., Floros, Joanna
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3027069/
https://ncbi.nlm.nih.gov/pubmed/21278811
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