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The Role of HDACs Inhibitors in Childhood and Adolescence Acute Leukemias

Acute leukemia is the most common type of childhood and adolescence cancer, characterized by clonal proliferation of variably differentiated myeloid or lymphoid precursors. Recent insights into the molecular pathogenesis of leukemia have shown that epigenetic modifications, such as deacetylation of...

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Bibliographic Details
Main Authors: Masetti, Riccardo, Serravalle, Salvatore, Biagi, Carlotta, Pession, Andrea
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3026992/
https://ncbi.nlm.nih.gov/pubmed/21318168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/148046
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