Genetic rescue of nonclassical ERα signaling normalizes energy balance in obese Erα-null mutant mice

In addition to its role in reproduction, estradiol-17β is critical to the regulation of energy balance and body weight. Estrogen receptor α–null (Erα(–/–)) mutant mice develop an obese state characterized by decreased energy expenditure, decreased locomotion, increased adiposity, altered glucose hom...

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Detalhes bibliográficos
Main Authors: Park, Cheryl J., Zhao, Zhen, Glidewell-Kenney, Christine, Lazic, Milos, Chambon, Pierre, Krust, Andrée, Weiss, Jeffrey, Clegg, Deborah J., Dunaif, Andrea, Jameson, J. Larry, Levine, Jon E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3026715/
https://ncbi.nlm.nih.gov/pubmed/21245576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI41702
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