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Skeletal Effects of Estrogen Are Mediated by Opposing Actions of Classical and Nonclassical Estrogen Receptor Pathways

ERα acts either through classical (ERE-mediated) or nonclassical (non-ERE) pathways. The generation of mice carrying a mutation that eliminates classical ERα signaling presents a unique opportunity to study the relative roles of these pathways in bone. This study defines the skeletal phenotype and r...

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Detalhes bibliográficos
Main Authors: Syed, Farhan A, Mödder, Ulrike IL, Fraser, Daniel G, Spelsberg, Thomas C, Rosen, Clifford J, Krust, Andree, Chambon, Pierre, Jameson, J Larry, Khosla, Sundeep
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1352155/
https://ncbi.nlm.nih.gov/pubmed/16234973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1359/JBMR.050713
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