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Cannabidiol attenuates cardiac dysfunction, oxidative stress, fibrosis, inflammatory and cell death signaling pathways in diabetic cardiomyopathy

OBJECTIVES: In this study, we have investigated the effects of cannabidiol (CBD) on myocardial dysfunction, inflammation, oxidative/nitrosative stress, cell death and interrelated signaling pathways, using a mouse model of type I diabetic cardiomyopathy and primary human cardiomyocytes exposed to hi...

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Hlavní autoři: Rajesh, Mohanraj, Mukhopadhyay, Partha, Bátkai, Sándor, Patel, Vivek, Saito, Keita, Matsumoto, Shingo, Kashiwaya, Yoshihiro, Horváth, Béla, Mukhopadhyay, Bani, Becker, Lauren, Haskó, György, Liaudet, Lucas, Wink, David A, Veves, Aristidis, Mechoulam, Raphael, Pacher, Pál
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3026637/
https://ncbi.nlm.nih.gov/pubmed/21144973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2010.07.033
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