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Role of superoxide, nitric oxide, and peroxynitrite in doxorubicin-induced cell death in vivo and in vitro

Doxorubicin (DOX) is a potent available antitumor agent; however, its clinical use is limited because of its cardiotoxicity. Cell death is a key component in DOX-induced cardiotoxicity, but its mechanisms are elusive. Here, we explore the role of superoxide, nitric oxide (NO), and peroxynitrite in D...

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Bibliografiset tiedot
Päätekijät: Mukhopadhyay, Partha, Rajesh, Mohanraj, Bátkai, Sándor, Kashiwaya, Yoshihiro, Haskó, György, Liaudet, Lucas, Szabó, Csaba, Pacher, Pál
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Physiological Society 2009
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685360/
https://ncbi.nlm.nih.gov/pubmed/19286953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00795.2008
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