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Novel chimeric thyroid-stimulating hormone-receptor bioassay for thyroid-stimulating immunoglobulins
Thyroid-stimulating immunoglobulins (TSI) are a functional biomarker of Graves' disease (GD). To develop a novel TSI bioassay, a cell line (MC4-CHO-Luc) was bio-engineered to constitutively express a chimeric TSH receptor (TSHR) and constructed with a cyclic adenosine monophosphate (cAMP)-depen...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Blackwell Science Inc
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3026547/ https://ncbi.nlm.nih.gov/pubmed/21070207 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2010.04266.x |
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