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A novel bioassay for anti-thyrotrophin receptor autoantibodies detects both thyroid-blocking and stimulating activity

Autoantibodies to the thyrotrophin (TSH) receptor (anti-TSHR) are unique, in that they are involved directly in the pathophysiology of certain autoimmune thyroid diseases (AITD). Thyroid-stimulating antibodies (TSAb) act as agonists that activate the thyroid gland and cause Graves' disease. Oth...

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Detalhes bibliográficos
Main Authors: Li, Y, Kim, J, Diana, T, Klasen, R, Olivo, P D, Kahaly, G J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2013
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949626/
https://ncbi.nlm.nih.gov/pubmed/23647395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12129
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