Isolation of Fully Human Antagonistic RON Antibodies Showing Efficient Block of Downstream Signaling and Cell Migration

RON belongs to the c-MET family of receptor tyrosine kinases. As its well-known family member MET, RON and its ligand macrophage-stimulating protein have been implicated in the progression and metastasis of tumors and have been shown to be overexpressed in cancer. We generated and tested a large num...

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Detalhes bibliográficos
Main Authors: Gunes, Zeynep, Zucconi, Adriana, Cioce, Mario, Meola, Annalisa, Pezzanera, Monica, Acali, Stefano, Zampaglione, Immacolata, De Pratti, Valeria, Bova, Luca, Talamo, Fabio, Demartis, Anna, Monaci, Paolo, La Monica, Nicola, Ciliberto, Gennaro, Vitelli, Alessandra
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3026407/
https://ncbi.nlm.nih.gov/pubmed/21286376
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