تحميل...
Acceleration of 5-Methylcytosine Deamination in Cyclobutane Dimers by G and its Implications for UV-induced C to T Mutation Hotspots
Sunlight-induced C→T mutation hotspots occur most frequently at methylated CpG sites in tumor suppressor genes and thought to arise from trans-lesion synthesis past deaminated cyclobutane pyrimidine dimers (CPDs). While it is known that methylation enhances CPD formation in sunlight, little is known...
محفوظ في:
| المؤلفون الرئيسيون: | , |
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| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
2009
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3026386/ https://ncbi.nlm.nih.gov/pubmed/19631218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.07.048 |
| الوسوم: |
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