Alphavirus Replicon-based Adjuvants Enhance the Immunogenicity and Effectiveness of Fluzone(®) in Rhesus Macaques

Venezuelan equine encephalitis virus replicon particles (VRP) without a transgene (null VRP) have been used to adjuvant effective humoral [1], cellular [2], and mucosal [3] immune responses in mice. To assess the adjuvant activity of null VRP in the context of a licensed inactivated influenza virus...

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Bibliografiske detaljer
Main Authors: Carroll, Timothy D, Matzinger, Shannon R, Barro, Mario, Fritts, Linda, McChesney, Michael B, Miller, Christopher J, Johnston, Robert E
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3026063/
https://ncbi.nlm.nih.gov/pubmed/21111777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2010.11.024
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