Exogenous IFN-alpha Administration Reduces Influenza A Virus Replication in the Lower Respiratory Tract of Rhesus Macaques

To determine the role of innate immune responses in controlling influenza A virus replication, rhesus macaques (RM) were administered pegylated IFN-alpha prior to virus challenge. Systemic and mucosal pegylated IFN-alpha administration induced expression of the interferon-stimulated genes (ISG) MxA...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Matzinger, Shannon R., Carroll, Timothy D., Fritts, Linda, McChesney, Michael B., Miller, Christopher J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2011
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248419/
https://ncbi.nlm.nih.gov/pubmed/22220209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029255
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak