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Sustained Delivery of Activated Rho GTPases and BDNF Promotes Axon Growth in CSPG-Rich Regions Following Spinal Cord Injury

BACKGROUND: Spinal cord injury (SCI) often results in permanent functional loss. This physical trauma leads to secondary events, such as the deposition of inhibitory chondroitin sulfate proteoglycan (CSPG) within astroglial scar tissue at the lesion. METHODOLOGY/PRINCIPAL FINDINGS: We examined wheth...

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Bibliografiske detaljer
Main Authors: Jain, Anjana, McKeon, Robert J., Brady-Kalnay, Susann M., Bellamkonda, Ravi V.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3026041/
https://ncbi.nlm.nih.gov/pubmed/21283639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016135
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