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Targeting choroid plexus epithelia and ventricular ependyma for drug delivery to the central nervous system

BACKGROUND: Because the choroid plexus (CP) is uniquely suited to control the composition of cerebrospinal fluid (CSF), there may be therapeutic benefits to increasing the levels of biologically active proteins in CSF to modulate central nervous system (CNS) functions. To this end, we sought to iden...

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Autori principali: Gonzalez, Ana Maria, Leadbeater, Wendy E, Burg, Michael, Sims, Karen, Terasaki, Tetsuya, Johanson, Conrad E, Stopa, Edward G, Eliceiri, Brian P, Baird, Andrew
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025905/
https://ncbi.nlm.nih.gov/pubmed/21214926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-12-4
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