Epidermal Growth Factor Targeting of Bacteriophage to the Choroid Plexus for Gene Delivery to the Central Nervous System via Cerebrospinal Fluid

Because the choroid plexus normally controls the production and composition of cerebrospinal fluid and as such, its many functions of the central nervous system, we investigated whether ligand-mediated targeting could deliver genes to its secretory epithelium. We show here that when bacteriophage ar...

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Detalhes bibliográficos
Main Authors: Gonzalez, Ana Maria, Podvin, Sonia, Leadbeater, Wendy, Borboa, Alexandra, Burg, Michael, Sawada, Ritsuko, Rayner, James, Sims, Karen, Terasaki, Tetsuya, Johanson, Conrad, Stopa, Edward, Eliceiri, Brian, Baird, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955767/
https://ncbi.nlm.nih.gov/pubmed/20732308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2010.08.044
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