Polymorphisms in the SULF1 gene are associated with early age of onset and survival of ovarian cancer

BACKGROUND: SULF1 (sulfatase 1) selectively removes the 6-O-sulphate group from heparan sulfate, changing the binding sites for extracellular growth factors. SULF1 expression has been reported to be decreased in various cancers, including ovarian cancer. We hypothesized that single nucleotide polymo...

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Detalhes bibliográficos
Main Authors: Han, Chan H, Huang, Yu-Jing, Lu, Karen H, Liu, Zhensheng, Mills, Gordon B, Wei, Qingyi, Wang, Li-E
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025876/
https://ncbi.nlm.nih.gov/pubmed/21214932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-30-5
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