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Transient inflammation-induced ongoing pain is driven by TRPV1 sensitive afferents

BACKGROUND: Tissue injury elicits both hypersensitivity to evoked stimuli and ongoing, stimulus-independent pain. We previously demonstrated that pain relief elicits reward in nerve-injured rats. This approach was used to evaluate the temporal and mechanistic features of inflammation-induced ongoing...

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Detalhes bibliográficos
Main Authors: Okun, Alec, DeFelice, Milena, Eyde, Nathan, Ren, Jiyang, Mercado, Ramon, King, Tamara, Porreca, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025866/
https://ncbi.nlm.nih.gov/pubmed/21219650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-7-4
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