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The tendency to recreate ancestral CG dinucleotides in the human genome
BACKGROUND: The CG dinucleotides are known to be deficient in the human genome, due to a high mutation rate from 5-methylated CG to TG and its complementary pair CA. Meanwhile, many cellular functions rely on these CG dinucleotides, such as gene expression controlled by cytosine methylation status....
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3025853/ https://ncbi.nlm.nih.gov/pubmed/21208429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-11-3 |
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