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CG dinucleotide clustering is a species-specific property of the genome
Cytosines at cytosine-guanine (CG) dinucleotides are the near-exclusive target of DNA methyltransferases in mammalian genomes. Spontaneous deamination of methylcytosine to thymine makes methylated cytosines unusually susceptible to mutation and consequent depletion. The loci where CG dinucleotides r...
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主要な著者: | , , , , , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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Oxford University Press
2007
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オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2175314/ https://ncbi.nlm.nih.gov/pubmed/17932072 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm489 |
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