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CG dinucleotide clustering is a species-specific property of the genome

Cytosines at cytosine-guanine (CG) dinucleotides are the near-exclusive target of DNA methyltransferases in mammalian genomes. Spontaneous deamination of methylcytosine to thymine makes methylated cytosines unusually susceptible to mutation and consequent depletion. The loci where CG dinucleotides r...

詳細記述

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書誌詳細
主要な著者: Glass, Jacob L., Thompson, Reid F., Khulan, Batbayar, Figueroa, Maria E., Olivier, Emmanuel N., Oakley, Erin J., Van Zant, Gary, Bouhassira, Eric E., Melnick, Ari, Golden, Aaron, Fazzari, Melissa J., Greally, John M.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175314/
https://ncbi.nlm.nih.gov/pubmed/17932072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm489
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